反应详情

To a two necked round bottomed flask with a reflux condenser is added 3-pentadecyl phenol, DMSO, sodium hydroxide followed by dropwise addition of alkylating agent such as methyl iodide with constant stirring at room temperature. The stirring is continued for about 6-8 hrs. The reaction mixture is then poured into deionized water and the organic matter is extracted in diethyl ether, separated the organic layer, washed with water and dried, purified to obtain 3-pentadecyl anisole.

1. additionfollowed by dropwise addition
2. extractionthe organic matter is extracted in diethyl ether
3. customseparated the organic layer
4. washwashed with water
5. customdried
6. custompurified