Hydrochloric Acid → HCID 23139185, compound

HRID 2279927Notes

Reaction equation

HRID 2279927 reaction equation
[CH:1]([C:3]1[CH:4]=[N:5][N:6]([CH2:8][C:9]([O:11]C(C)(C)C)=[O:10])[CH:7]=1)=[O:2].Cl>O1CCOCC1>[CH:1]([C:3]1[CH:4]=[N:5][N:6]([CH2:8][C:9]([OH:11])=[O:10])[CH:7]=1)=[O:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 889754691793069-27-8

Product 1

HCID 23139185HCID 23139185, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent2×

Procedure

To a solution of tert-butyl 2-(4-formylpyrazol-1-yl)acetate (0.67 g, 3.19 mmol) in dioxane (10 mL) was added a 4N solution of HCl in dioxane (10 mL) and the mixture was stirred at room temperature for three days. The solvent was removed by evaporation under reduced pressure to afford the title compound (0.41 g, 98%) as a yellow oil.

Workup

  1. customThe solvent was removed by evaporation under reduced pressure

Sources & evidence

ORD record
ord-10429221aa0a4db19a04a6f84c8f3332
Source dataset
uspto-grants-2015_09
Patent number
US09133185B2

Reaction notes

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