反应详情

To sodium [123I] iodide, received in 5-20 μL 0.05M sodium hydroxide is added ammonium acetate buffer (100 μL pH 4.0, 0.2M), sodium [127I] iodide (10 μL, 1 mM solution in 0.01M sodium hydroxide, 1×10−8 moles), peracetic acid (PAA) solution (10 μL 1 mM solution, 1×10−8 moles) and finally 10-(4-tributylstannyl-[1,2,3]triazol-1-yl)-decanoic acid solution in ethanol or acetonitrile (53 μg, 1×10−7 moles). The reaction mixture is allowed to stand at room temperature for 15 minutes prior to HPLC purification of the iodinated product 10-(4-iodo-[1,2,3]triazol-1-yl)-decanoic acid.

1. customto HPLC purification of the iodinated product 10-(4-iodo-[1,2,3]triazol-1-yl)-decanoic acid