Dimethylamine → N,N-Dimethyl-5,5-diphenylpent-4-en-1-amine

HRID 2283148Notes

Reaction equation

HRID 2283148 reaction equation
[CH3:1][NH:2][CH3:3].Br[CH2:5][CH2:6][CH2:7][CH:8]=[C:9]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>C1COCC1>[CH3:1][N:2]([CH2:5][CH2:6][CH2:7][CH:8]=[C:9]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1)[CH3:3]

Participants

4

Reactant 2

HCID 674DimethylamineHCID 155508755,5-Diphenyl-4-pentenyl bromide

Product 1

HCID 20321002N,N-Dimethyl-5,5-diphenylpent-4-en-1-amine

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Next, an aqueous solution (40%) of dimethyl amine (25 equivalents) is added slowly to a THF solution of 1.0 equivalent of 5-bromo-1,1-diphenyl-1-pentene that has been obtained in the previous step. The mixture is then stirred at room temperature for 24 hours, and worked up in the usual manner to yield 5-(N,N-dimethyl)amino-1,1-diphenyl-1-pentene as a yellow oil.

Workup

  1. customhas been obtained in the previous step

Sources & evidence

ORD record
ord-1cc52e4cede243de9d42f18fbaf49008
Source dataset
uspto-grants-2015_09
Patent number
US09145352B2

Reaction notes

Loading…