(Z)-Benzaldehyde oxime → N-hydroxybenzenecarboximidoyl chloride

HRID 2283854Notes

Reaction equation

HRID 2283854 reaction equation
[CH:1](=[N:8][OH:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:10]N1C(=O)CCC1=O>CN(C=O)C>[Cl:10][C:1](=[N:8][OH:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 12143(Z)-Benzaldehyde oximeHCID 31398Chlorosuccinimide

Product 1

HCID 2756315N-hydroxybenzenecarboximidoyl chlorideYield 93%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

α-Chlorobenzaldoxime was prepared according to the method described in Part A of Example 595 by reacting benzaldoxime (11.5 g, 94.9 mmol) in DMF (20 mL) with N-chlorosuccinimide (12.6 g, 94.9 mmol). α-Chlorobenzaldoxime (13.7 g, 93%) was obtained as a white solid.

Workup

  1. customα-Chlorobenzaldoxime was prepared

Sources & evidence

ORD record
ord-716b906acab0410d9eba2aef23c03553
Source dataset
uspto-grants-2015_09
Patent number
US09145410B2

Reaction notes

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