Methylamine → HCID 89442776, compound

HRID 2283934Notes

Reaction equation

HRID 2283934 reaction equation
Cl[C:2]1[C:7]([Cl:8])=[C:6]([Cl:9])[N:5]=[CH:4][N:3]=1.[CH3:10][NH2:11]>CC(O)C>[Cl:8][C:7]1[C:2]([NH:11][CH3:10])=[N:3][CH:4]=[N:5][C:6]=1[Cl:9]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 2490074,5,6-Trichloropyrimidine

Product 1

HCID 89442776HCID 89442776, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

4,5,6-trichloropyrimidine 3a was reacted with aqueous methylamine in 2-propanol to afford 5,6-dichloro-N-methylpyrimidin-4-amine 3b.

Sources & evidence

ORD record
ord-fe060484276344419c904ca11e7d7e97
Source dataset
uspto-grants-2015_09
Patent number
US09145392B2

Reaction notes

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