HRID2286014

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7993

3-(Dimethylamino)propylamine

C5H14N2

$结构：CC(C)OC(=O)/C=C\C(=O)O$

HCID6436106

Isopropyl hydrogen maleate

C7H10O4

PRODUCTS

生成物

HCID54445499

未命名化合物

收率 94.7%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8471

Triethylamine

C6H15N

PROCEDURE

实验过程

395.2 g (2.5 mols) of maleic acid-monoisopropyl ester, 500 ml of triethylamine and 306.5 g (2.5 mols+20% excess) of 3-dimethylaminopropylamine are reacted according to Example 1, and the reaction product is subsequently purified to yield 616.4 g (94.7% of theory) of a white crystalline aspartic acid derivative of which the melting point is 163.5°-165.5° C.

WORKUP

后处理

customthe reaction product is subsequently purified