Piperidine-1-propylamine → HCID 22819943, compound

HRID 2286018Notes

Reaction equation

HRID 2286018 reaction equation
[CH3:1][O:2][C:3](=[O:9])/[CH:4]=[CH:5]\[C:6]([OH:8])=[O:7].[NH2:10][CH2:11][CH2:12][CH2:13][N:14]1[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>C(N(CC)CC)C>[CH3:1][O:2][C:3](=[O:9])[CH2:4][C@@H:5]([C:6]([OH:8])=[O:7])[NH:10][CH2:11][CH2:12][CH2:13][N:14]1[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1

Participants

4

Reactant 2

HCID 19049Piperidine-1-propylamineHCID 5354456Monomethyl maleate

Product 1

HCID 22819943HCID 22819943, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

In a manner analogous to that described in Example 1, 28.6 g (0.2 mol+10% excess) of maleic acid-monomethyl ester, 40 ml of triethylamine and 88.4 g (0.2 mol) of N-(3'-aminopropyl)-piperidine are reacted and the reaction product is purified. The yield is 36.7 g (67.4% of theory) and the melting point of the product obtained is 172°-173° C.

Workup

  1. customare reacted
  2. customthe reaction product is purified
  3. customThe yield is 36.7 g (67.4% of theory) and the melting point of the product obtained
  4. customis 172°-173° C.

Sources & evidence

ORD record
ord-58c40167037f40a9b2ad44c3827b91bb
Source dataset
uspto-grants-1982_04
Patent number
US04326069

Reaction notes

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