Phenyl isocyanate → HCID 86737666, compound

HRID 2286045Notes

Reaction equation

HRID 2286045 reaction equation
[Cl:1][CH2:2][C:3]([N:5]([C:12]1[C:17]([CH3:18])=[CH:16][CH:15]=[CH:14][C:13]=1[CH3:19])[CH:6]([CH3:11])[C:7](=[N:9][OH:10])[CH3:8])=[O:4].[C:20]1([N:26]=[C:27]=[O:28])[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>C(N(CC)CC)C.C(Cl)Cl>[C:20]1([NH:26][C:27]([O:10][N:9]=[C:7]([CH:6]([N:5]([C:12]2[C:13]([CH3:19])=[CH:14][CH:15]=[CH:16][C:17]=2[CH3:18])[C:3](=[O:4])[CH2:2][Cl:1])[CH3:11])[CH3:8])=[O:28])[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

5

Reactant 2

HCID 7672Phenyl isocyanateHCID 73683068HCID 73683068, compound

Product 1

HCID 86737666HCID 86737666, compound

Reagents, catalysts & solvents 2

HCID 8471TriethylamineCatalystHCID 6344DichloromethaneSolvent

Procedure

Following the procedure of Example 11, 3 g of 3-(N-chloroacetyl-2,6-dimethylphenylamino)-2-butanone oxime, 3 g phenylisocyanate and 5 drops triethylamine in 100 ml methylene chloride were stirred, refluxed and worked up to yield the title product, m.p. 115°-117° C. This product is tabulated as Compound No. 18 in Table I.

Workup

  1. temperaturerefluxed

Sources & evidence

ORD record
ord-91137e9e75374b0c973c9c9507204ac4
Source dataset
uspto-grants-1982_04
Patent number
US04326077

Reaction notes

Loading…