Hydrochloric Acid → HCID 12831639, compound

HRID 2286192Notes

Reaction equation

HRID 2286192 reaction equation
[CH2:1]([N:4]1[C:9](=[O:10])[N:8]=[C:7](SC)[CH:6]=[N:5]1)[CH:2]=[CH2:3].Cl.C([OH:16])C>>[CH2:1]([N:4]1[C:9](=[O:10])[NH:8][C:7](=[O:16])[CH:6]=[N:5]1)[CH:2]=[CH2:3]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 12836706HCID 12836706, compound

Product 1

HCID 12831639HCID 12831639, compoundYield 84.8%

Procedure

A mixture of 1.49 g 2-allyl-3-oxo-5-methylthio-2,3-dihydro-1,2,4-triazine, 6 ml conc. hydrochloric acid and 12 ml ethyl alcohol was heated under reflux for 1.5 hours. After cooling to room temperature, the solvent was removed under reduced pressure to obtain a yellow solid. This solid was recrystallized from ethyl alcohol to obtain 1.06 g of a white crystal.

Workup

  1. temperaturewas heated
  2. temperatureunder reflux for 1.5 hours
  3. customthe solvent was removed under reduced pressure
  4. customto obtain a yellow solid
  5. customThis solid was recrystallized from ethyl alcohol

Sources & evidence

ORD record
ord-9f8d8784f1314fdb92de2c998aeeb7c8
Source dataset
uspto-grants-1982_04
Patent number
US04327094

Reaction notes

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