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HRID2286325

反应详情

EQUATION

反应方程式

HRID 2286325 的结构方程式

REACTANTS

反应物

2
结构：O=C(OO)c1cccc(Cl)c1
HCID70297

Benzenecarboperoxoic acid, 3-chloro-

C7H5ClO3

结构：CCSC1=C(Cl)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C
HCID70562795

未命名化合物

PRODUCTS

生成物

1
结构：CCS(=O)C1=C(Cl)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C
HCID70563103

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

2 次

PROCEDURE

实验过程

To (11β)-16-chloro-17-(ethylthio)-9-fluoro-11-hydroxyandrosta-1,4,16-trien-3-one (100 mg; see Example 1A) in dichloromethane (15 ml) is added a solution of 85% m-chloroperbenzoic acid (56 mg) in dichloromethane (5.0 ml) over a period of 2 minutes. After 1 hour the solution is washed with a dilute sodium carbonate solution and water, dried (anhydrous MgSO4) and evaporated to yield the title compound.

WORKUP

后处理

  1. washAfter 1 hour the solution is washed with a dilute sodium carbonate solution and water
  2. dry with materialdried (anhydrous MgSO4)
  3. customevaporated