Hydrochloric Acid → HCID 23463333, compound

HRID 2286423Notes

Reaction equation

HRID 2286423 reaction equation
[F:1][C:2]([F:16])([F:15])[CH2:3][N:4]1[C:8](=[O:9])[CH2:7][C:6]([C:10](OCC)=[O:11])=[N:5]1.Cl.[OH-].[NH4+:19]>>[F:1][C:2]([F:16])([F:15])[CH2:3][N:4]1[C:8](=[O:9])[CH2:7][C:6]([C:10](=[O:11])[NH2:19])=[N:5]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 14923Ammonium HydroxideHCID 23463328HCID 23463328, compound

Product 1

HCID 23463333HCID 23463333, compound

Procedure

0.71 Mole (169 g) of 1-(2',2',2'-trifluoroethyl)-3-carbethoxy-2-pyrazolin-5-one were stirred for 8 hours in concentrated ammonium hydroxide and left standing afterwards for 5 days in a sealed recipient at room temperature. After filtration the filtrate obtained was poured out on ice and acidified with hydrochloric acid. As soon as the product had crystallized out completely, it was filtered and washed with water.

Workup

  1. waitleft
  2. filtrationAfter filtration the filtrate
  3. customobtained
  4. additionwas poured out on ice
  5. customAs soon as the product had crystallized out completely
  6. filtrationit was filtered
  7. washwashed with water

Sources & evidence

ORD record
ord-ce4e832953064770a4e7f76f6ff1172f
Source dataset
uspto-grants-1981_05
Patent number
US04266014

Reaction notes

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