Triethylamine → HCID 23462554, compound

HRID 2286760Notes

Reaction equation

HRID 2286760 reaction equation
[CH2:1]=[CH:2][C:3](=[O:9])[CH2:4][CH2:5][CH2:6][CH:7]=[CH2:8].[CH3:10][CH:11]1[C:16](=[O:17])[CH2:15][CH2:14][CH2:13][C:12]1=[O:18].C(N(CC)CC)C>C(OCC)(=O)C>[CH3:10][C:11]1([CH2:1][CH2:2][C:3](=[O:9])[CH2:4][CH2:5][CH2:6][CH:7]=[CH2:8])[C:16](=[O:17])[CH2:15][CH2:14][CH2:13][C:12]1=[O:18]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 709452-Methyl-1,3-cyclohexanedioneHCID 118047521,7-octadien-3-one

Product 1

HCID 23462554HCID 23462554, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

1,7-Octadien-3-one(0.24 g), 2-methyl-1,3-cyclohexanedione(0.5 g) and triethylamine (1 ml) are added to ethyl acetate (10 ml), and the mixture is stirred at room temperature for 24 hours. The triethylamine and acetic acid are evaporated off and the residue is purified by silica gel column chromatography(methylene chloride) to recover 0.39 g of the above-indicated compound. [IR 1700-1730 cm-1, 920 cm-1 ; NMR 1.10 ppm(3H, singlet, --CH3), 4.6-6.0 ppm(3H, multiplet, vinyl)].

Workup

  1. customThe triethylamine and acetic acid are evaporated off
  2. customthe residue is purified by silica gel column chromatography(methylene chloride)
  3. customto recover 0.39 g of the above-indicated compound

Sources & evidence

ORD record
ord-4f38ba43deb04cac9a2e07775cec7896
Source dataset
uspto-grants-1981_05
Patent number
US04267377

Reaction notes

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