Phenol → 2-Isopropylphenol

HRID 2286786Notes

Reaction equation

HRID 2286786 reaction equation
[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:8](O)([CH3:10])[CH3:9].B(F)(F)F>P(=O)(O)(O)O>[CH:8]([C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][C:1]=1[OH:7])([CH3:10])[CH3:9]

Participants

5

Reactant 3

HCID 996PhenolHCID 3776IsopropanolHCID 6356Boron trifluoride

Product 1

HCID 69432-Isopropylphenol

Reagents, catalysts & solvents 1

HCID 1004Phosphoric AcidSolvent

Procedure

A process according to claim 1 wherein phenol is reacted with isopropanol in the presence of a diethyl ether complex of boron trifluoride in phosphoric acid diluent at a temperature of between about 70°-90° C. to produce ortho-isopropyl phenol.

Sources & evidence

ORD record
ord-e8ee329898f745a28ccf62b61335ac3c
Source dataset
uspto-grants-1981_05
Patent number
US04267394

Reaction notes

Loading…