Ethyl Bromide → HCID 23460465, compound

HRID 2286836Notes

Reaction equation

HRID 2286836 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH2:11]Br)=[CH:4][CH:3]=1.[P:13]([O:20]CC)([O:17][CH2:18][CH3:19])[O:14][CH2:15][CH3:16].C(Br)C>O>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH2:11][P:13](=[O:20])([O:17][CH2:18][CH3:19])[O:14][CH2:15][CH3:16])=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 6332Ethyl BromideHCID 31215Triethyl phosphiteHCID 22913727HCID 22913727, compound

Product 1

HCID 23460465HCID 23460465, compoundYield 78%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 12.38 g of 4(p-chlorophenyl)butyl bromide and 20 g of triethyl phosphite was refluxed at 160° for seven hours. During this period the circulating water in the condenser was maintained at 50° to allow the ethyl bromide to distill off. After removal of the excess of triethyl phosphite, distillation under reduced pressure gave 11.9 g (39 mmol) of a white viscuous oil.

Workup

  1. temperaturewas refluxed at 160° for seven hours
  2. distillationto distill off
  3. customAfter removal of the
  4. distillationexcess of triethyl phosphite, distillation under reduced pressure

Sources & evidence

ORD record
ord-6e5c8cc9bc3d44d69faa815653f49241
Source dataset
uspto-grants-1981_05
Patent number
US04268507

Reaction notes

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