反应详情

32 g of 2-[2'(2-methoxyethoxy)-5'-nitrobenzenesulfonamido]-4-hexadecyloxy-5-methylphenol prepared as described in Step (b) above, 24 g of iron powder, 12 g of Fe2O4, 0.6 g of ammonium chloride and 25 ml of water were added to 300 ml of isopropyl alcohol and the mixture was refluxed on a stream bath with stirring for 1 hour. After completion of the reaction, the mixture was filtered while hot and the filtrate was cooled with ice. The crystals thus precipitated were recovered by filtration, washed with 50 ml of isopropyl alcohol and air-dried. Yield: 23 g; Melting Point: 142°to 144° C.

1. temperaturethe mixture was refluxed on a stream bath
2. customAfter completion of the reaction
3. filtrationthe mixture was filtered while hot and the filtrate
4. temperaturewas cooled with ice
5. customThe crystals thus precipitated
6. filtrationwere recovered by filtration
7. washwashed with 50 ml of isopropyl alcohol
8. customair-dried
9. custom142°to 144° C.