HCID 23459882, compound → HCID 23459883, compound

HRID 2287215Notes

Reaction equation

HRID 2287215 reaction equation
[Cl:1][C:2]1[CH:20]=[CH:19][C:18]([C:21]([O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])=[O:22])=[CH:17][C:3]=1[NH:4][C:5](=[O:16])[CH:6](Cl)[C:7](=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.[K].[C:39]1(=[O:49])[NH:43][C:42](=[O:44])[C:41]2=[CH:45][CH:46]=[CH:47][CH:48]=[C:40]12>CN(C)C=O>[Cl:1][C:2]1[CH:20]=[CH:19][C:18]([C:21]([O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])=[O:22])=[CH:17][C:3]=1[NH:4][C:5](=[O:16])[CH:6]([C:7](=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[N:43]1[C:42](=[O:44])[C:41]2=[CH:45][CH:46]=[CH:47][CH:48]=[C:40]2[C:39]1=[O:49]

Participants

4

Reactant 2

HCID 23459882HCID 23459882, compoundHCID 24194345Phthalimide potassium salt

Product 1

HCID 23459883HCID 23459883, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture of 16.3 g of 2'-chloro-5'-tetradecyloxycarbonylchloro-benzoylacetanilide and 18.5 g of phthalimide potassium was stirred in 300 ml of dimethylformamide for 3 hours at room temperature. The reaction product thus obtained was treated as in Synthesis example 1. Upon recrystallizing the product from methanol, 12 g of Coupler 6 having a melting point of 81°-82° C. was obtained.

Workup

  1. customThe reaction product thus obtained
  2. additionwas treated as in Synthesis example 1
  3. customUpon recrystallizing the product from methanol, 12 g of Coupler 6 having a melting point of 81°-82° C.
  4. customwas obtained

Sources & evidence

ORD record
ord-7bb93c66faab4593ba41579af29e0371
Source dataset
uspto-grants-1981_05
Patent number
US04269936

Reaction notes

Loading…