Hydrochloric Acid → Methyl 6-hydroxy-2-naphthoate

HRID 2287942Notes

Reaction equation

HRID 2287942 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([C:12]([OH:14])=[O:13])[CH:6]=[CH:5]2.Cl.[CH3:16]O>>[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([C:12]([O:14][CH3:16])=[O:13])[CH:6]=[CH:5]2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 855576-Hydroxy-2-naphthoic acid

Product 1

HCID 390995Methyl 6-hydroxy-2-naphthoate

Procedure

6-Hydroxy-2-naphthoic acid is heated under reflux for 2 h in anhydrous methanol which had previously been saturated with HCl gas. The mixture is concentrated, the residue is recrystallized once each from methanol and from acetone and methyl 6-hydroxy-2-naphthoate is obtained.

Workup

  1. concentrationThe mixture is concentrated
  2. customthe residue is recrystallized once each from methanol

Sources & evidence

ORD record
ord-c84c9e591f6f45769f7a670f694b0124
Source dataset
uspto-grants-2000_07
Patent number
US06087304

Reaction notes

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