4-Chlorobenzaldehyde → HCID 18699634, compound

HRID 2288584Notes

Reaction equation

HRID 2288584 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]([CH2:6][CH2:7][NH2:8])=[CH:2]1.[Cl:9][C:10]1[CH:17]=[CH:16][C:13]([CH:14]=O)=[CH:12][CH:11]=1>>[Cl:9][C:10]1[CH:17]=[CH:16][C:13]([CH:14]2[C:2]3[S:1][CH:5]=[CH:4][C:3]=3[CH2:6][CH2:7][NH:8]2)=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 77264-ChlorobenzaldehydeHCID 122587372-(3-Thienyl)ethanamine

Product 1

HCID 18699634HCID 18699634, compound

Procedure

2-(3-Thienyl)ethanamine (3.15 g) and 4-chlorobenzaldehyde (3.5 g) were mixed without solvent resulting in dissolution af the crystals of the amine followed by precipitation of slightly yellow crystals. The mixture was left at RT for 4 h. Trifluoroacetic acid (20 ml) was added and the mixture stirred overnight at RT.

Sources & evidence

ORD record
ord-9d76cd298f714f50ac06c2ebe00be5bc
Source dataset
uspto-grants-2000_07
Patent number
US06090797

Reaction notes

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