Sodium Bicarbonate → HCID 18432837, compound

HRID 2288665Notes

Reaction equation

HRID 2288665 reaction equation
[N:1]([O-:3])=O.[Na+].[NH2:5][C:6]1[N:11]([CH2:12][C:13]2[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=2)[C:10](=[O:19])[NH:9][C:8](=[O:20])[CH:7]=1.C(=O)(O)[O-].[Na+]>O.Cl>[NH2:5][C:6]1[N:11]([CH2:12][C:13]2[CH:14]=[CH:15][N:16]=[CH:17][CH:18]=2)[C:10](=[O:19])[NH:9][C:8](=[O:20])[C:7]=1[N:1]=[O:3]

Participants

6

Reactant 3

HCID 516892Sodium BicarbonateHCID 1526623HCID 1526623, compoundHCID 23668193Sodium Nitrite

Product 1

HCID 18432837HCID 18432837, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 962WaterSolvent

Procedure

2.6 ml of 4N sodium nitrite was added to a solution of 2.35 g of 6-amino-1-(4-picolyl)-uracil in 25 ml of water and 4 ml of 5N HCl. After 15 minutes, 10 ml of 1N sodium bicarbonate was added. The solid was collected, washed and dried to give the title compound (2.15 g).

Workup

  1. customThe solid was collected
  2. washwashed
  3. customdried

Sources & evidence

ORD record
ord-87a70b11d2b64d398cfb8acfd48f74fb
Source dataset
uspto-grants-2000_07
Patent number
US06090816

Reaction notes

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