Bromine → HCID 20231962, Verbindung

HRID 2290224Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2290224
[Br:1]Br.[C:3]([C:6]1[CH:7]=[C:8]2[C:12](=[CH:13][CH:14]=1)[C:11](=[O:15])[CH:10]([CH3:16])[CH2:9]2)([OH:5])=[O:4]>C(O)(=O)C>[Br:1][C:10]1([CH3:16])[CH2:9][C:8]2[C:12](=[CH:13][CH:14]=[C:6]([C:3]([OH:5])=[O:4])[CH:7]=2)[C:11]1=[O:15]

Komponenten

4

Edukt 2

HCID 24408BromineHCID 20231959HCID 20231959, Verbindung

Produkt 1

HCID 20231962HCID 20231962, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

Bromine (0.57 ml) was added dropwise during 15 minutes to a stirred solution of 5-carboxy-2-methylindan-1-one (2 g) in acetic acid (75 ml) at 35° C. The solution was stirred for a further 30 minutes then evaporated to low volume under reduced pressure and the residue was diluted with water to give 2-bromo-5-carboxy-2-methylindan-1-one, m.p. 203°-205° C. (from acetic acid).

Aufarbeitung

  1. customthen evaporated to low volume under reduced pressure
  2. additionthe residue was diluted with water

Quellen und Nachweise

ORD-Eintrag
ord-135ab8f5e9294b84af5aa6c1e9e99184
Quelldatensatz
uspto-grants-1986_10
Patentnummer
US04616013

Notizen zur Reaktion

Wird geladen…