Hydrazine hydrate (1:1) → HCID 15586409, compound

HRID 2290341Notes

Reaction equation

HRID 2290341 reaction equation
[CH3:1][C:2]1[N:3]=[C:4](SC)[N:5]=[N:6][C:7]=1[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.O.[NH2:17][NH2:18]>C(O)C>[NH:17]([C:4]1[N:5]=[N:6][C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[C:2]([CH3:1])[N:3]=1)[NH2:18]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 15586342HCID 15586342, compound

Product 1

HCID 15586409HCID 15586409, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 5-methyl-3-methylthio-6-phenyl-1,2,4-triazine (7 g) and hydrazine hydrate (5 ml) in ethanol (15 ml) was heated under reflux for 8 hours. The reaction mixture was evaporated and the resultant residue was washed with water, dried and recrystallized from a mixture of ethanol and water (5:3) to give crystals of 3-hydrazino-5-methyl-6-phenyl-1,2,4-triazine (3.76 g), m.p. 136.5°~137.5° C.

Workup

  1. temperatureunder reflux for 8 hours
  2. customThe reaction mixture was evaporated
  3. washthe resultant residue was washed with water
  4. customdried
  5. customrecrystallized from a mixture of ethanol and water (5:3)

Sources & evidence

ORD record
ord-a499cfd863824258a090fe07a3882d82
Source dataset
uspto-grants-1986_10
Patent number
US04616014

Reaction notes

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