Hydrazine hydrate (1:1) → HCID 20232011, compound

HRID 2290361Notes

Reaction equation

HRID 2290361 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[N:12][C:11](SC)=[N:10][C:9]=2[CH3:16])=[CH:4][CH:3]=1.O.[NH2:18][NH2:19]>C(O)C>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[N:12][C:11]([NH:18][NH2:19])=[N:10][C:9]=2[CH3:16])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20232094HCID 20232094, compound

Product 1

HCID 20232011HCID 20232011, compoundYield 15%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 6-(4-chlorophenyl)-5-methyl-3-methylthio-1,2,4-triazine (32.4 g) and hydrazine hydrate (40.8 g) in ethanol (110 ml) was heated for 2 hours. After cooling, the precipitates were collected by filtration, washed with ethanol, dried and recrystallized from ethanol to give 6-(4-chlorophenyl)-3-hydrazino-5-methyl-1,2,4-triazine (4.54 g).

Workup

  1. temperatureAfter cooling
  2. filtrationthe precipitates were collected by filtration
  3. washwashed with ethanol
  4. customdried
  5. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-e3980300259b431ab5fe7c237b2fef2a
Source dataset
uspto-grants-1986_10
Patent number
US04616014

Reaction notes

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