Potassium Carbonate → 2-Morpholinoethylamine

HRID 2290649Notes

Reaction equation

HRID 2290649 reaction equation
C(=O)([O-])[O-].[K+].[K+].CC1[C:14](=[O:15])[C:13]2[N:16]3[C@@:20](OC)([C@H](COC(N)=O)C=2C(=O)C=1OC)[C@H:19]1[NH:29][C@H:18]1[CH2:17]3>>[NH2:29][CH2:18][CH2:17][N:16]1[CH2:13][CH2:14][O:15][CH2:19][CH2:20]1

Participants

3

Reactant 2

HCID 11430Potassium CarbonateHCID 19972Mitomycin A

Product 1

HCID 4082852-Morpholinoethylamine

Procedure

This compound was prepared by the procedure described in Example 1, exept that the potassium carbonate was omitted. From 100 mg. of mitomycin A and 0.5 ml. of N-(2-aminoethyl)morpholine was obtained 70 mg. (55% yield) of the desired product having a melting point of 74°-76° C. (decomposition) and providing the following analysis:

Workup

  1. customThis compound was prepared by the procedure

Sources & evidence

ORD record
ord-02bc67d05d724b82b7364f3c797d6082
Source dataset
uspto-grants-1986_10
Patent number
US04617389

Reaction notes

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