反应详情

温度

110 °C

A solution of 6-(4-aminophenyl)-5-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one (2 g) and methylisothiocyanate (0.788 g) in dimethylformamide (20 ml) was heated with stirring at 110° C. for 4 hours, followed by after-treatment in the same manner as Example 8 to give 6-[4-(3-methyl-thioureido)phenyl]-5-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one (2.7 g).