Hydrochloric Acid → HCID 20230180, compound

HRID 2290746Notes

Reaction equation

HRID 2290746 reaction equation
C([NH:4][C:5]1[CH:10]=[CH:9][C:8]([C:11](=[N:16][NH:17][C:18]([NH2:20])=[S:19])[C:12](=NO)[CH3:13])=[CH:7][CH:6]=1)(=O)C.C(=O)([O-])[O-].[K+].[K+].Cl>O>[NH2:4][C:5]1[CH:6]=[CH:7][C:8]([C:11]2[C:12]([CH3:13])=[N:20][C:18](=[S:19])[NH:17][N:16]=2)=[CH:9][CH:10]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 11430Potassium CarbonateHCID 136332163HCID 136332163, compound

Product 1

HCID 20230180HCID 20230180, compoundYield 72.3%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 4'-acetamido-2-hydroxyiminopropiophenone thiosemicarbazone (5 g) and potassium carbonate (5.2 g) in water (40 ml) was refluxed for 24 hours and treated with activated carbon. The filtrate was acidified with diluted hydrochloric acid and the crystals which formed were recovered by filtration, washed with water and dried to give 6-(4-aminophenyl)-5-methyl-1,2,4-triazin-3(2H)-thione (2.69 g).

Workup

  1. additiontreated with activated carbon
  2. customthe crystals which formed
  3. filtrationwere recovered by filtration
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-ca2f0f5f6af14460b9733d3706a649ed
Source dataset
uspto-grants-1986_10
Patent number
US04618610

Reaction notes

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