Water → HCID 86742663, compound

HRID 2291612Notes

Reaction equation

HRID 2291612 reaction equation
Cl[C:2]1C2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[O:5][CH:4]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:3]=1C=O.O[CH:21]1[CH2:26]S[CH:24]([OH:27])[CH2:23][S:22]1.C(N(CC)CC)C.O>N1C=CC=CC=1>[C:12]1([CH:4]2[C:3]3[CH:2]=[C:23]([CH:24]=[O:27])[S:22][C:21]=3[C:26]3[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=3[O:5]2)[CH:13]=[CH:14][CH2:15][CH2:16][CH:17]=1

Participants

6

Reactant 4

HCID 962WaterHCID 8471TriethylamineHCID 983301,4-Dithiane-2,5-diolHCID 13393783HCID 13393783, compound

Product 1

HCID 86742663HCID 86742663, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent2×

Procedure

To a suspension of 4.2 g 4-chloro-3-formyl-flav-3-ene in 10 ml pyridine is added a solution of 2.6 g 2,5-dihydroxy-1,4-dithian and 2.2 g triethylamine in 11 ml pyridine. After overnight stirring one adds slowly 100 ml water and the precipitate is collected, washed with water, dried, and crystallized in absolute ethanol. Pure 4H-4-phenyl-thieno[3,2-c][1]benzopyran-2-carboxaldehyde is obtained; m.p. 117°-118° C.

Workup

  1. customthe precipitate is collected
  2. washwashed with water
  3. customdried
  4. customcrystallized in absolute ethanol

Sources & evidence

ORD record
ord-6c762c8fcb4641dea34fda4e5f61383a
Source dataset
uspto-grants-1989_01
Patent number
US04797414

Reaction notes

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