Hydrogen Bromide → HCID 13561737, compound

HRID 2291889Notes

Reaction equation

HRID 2291889 reaction equation
[CH3:1][C:2]([CH3:9])([CH2:6][CH:7]=[CH2:8])[C:3](=[O:5])[CH3:4].[BrH:10]>C(Cl)(Cl)Cl.[Fe]>[Br:10][CH:7]([CH3:8])[CH2:6][C:2]([CH3:9])([CH3:1])[C:3](=[O:5])[CH3:4]

Participants

5

Reactant 2

HCID 260Hydrogen BromideHCID 126041733,3-Dimethylhex-5-en-2-one

Product 1

HCID 13561737HCID 13561737, compoundYield 87%

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 6212ChloroformSolvent

Procedure

18.9 g (0.15 mole) of 3,3-dimethyl-5-hexen-2-one and 1.6 g (0.0054 mole) of iron-III bromide are dissolved in 150 ml of chloroform. 0.16 mole of hydrogen bromide gas are passed in at 0° C. in the course of 90 minutes. The mixture is subsequently stirred at room temperature for 2 hours and the organic phase is separated off, washed with water, dried over sodium sulphate and concentrated in vacuo. 27 g (87% of theory) of 5-bromo-3,3-dimethyl-2-hexanone of refractive index nD20 =1.4639 are obtained.

Workup

  1. customare passed in at 0° C. in the course of 90 minutes
  2. customthe organic phase is separated off
  3. washwashed with water
  4. dry with materialdried over sodium sulphate
  5. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-e626ccc5fbc049c29a6490f7a6c71ca6
Source dataset
uspto-grants-1989_01
Patent number
US04798899

Reaction notes

Loading…