HRID2292051

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID5238

Sodium Iodide

INa

HCID6342

Acetonitrile

C2H3N

HCID11430

Potassium Carbonate

CK2O3

结构：CC(=O)OCC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)[C@@H](NC(N)=S)[C@H]2SC1

HCID14349717

未命名化合物

PRODUCTS

生成物

结构：CC(=O)OCC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)[C@@H](Nc3nc(C)cs3)[C@H]2SC1

HCID14349730

未命名化合物

PROCEDURE

实验过程

A mixture of 91 mg of (6R-trans)-3-[(acetyloxyl)methyl]-7-[(aminothioxomethyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, diphenylmethyl ester, 33 mg of sodium iodide, 20 mg of potassium carbonate and 2 ml of acetonitrile was reacted as described in Example 2, giving the desired compound.

WORKUP

后处理

customwas reacted

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-fc9f69230cd548c2abbb4398d9f6fa6f
来源数据集: uspto-grants-1989_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04800199
来源说明: uspto-grants-1989_01

反应 SMILES

[C:1]([O:4][CH2:5][C:6]1[CH2:13][S:12][C@H:11]2[N:8]([C:9](=[O:18])[C@H:10]2[NH:14][C:15]([NH2:17])=[S:16])[C:7]=1[C:19]([O:21][CH:22]([C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)=[O:20])(=[O:3])[CH3:2].[I-].[Na+].[C:37](=O)([O-])[O-].[K+].[K+].[C:43](#N)[CH3:44]>>[C:1]([O:4][CH2:5][C:6]1[CH2:13][S:12][C@H:11]2[N:8]([C:9](=[O:18])[C@H:10]2[NH:14][C:15]2[S:16][CH:37]=[C:43]([CH3:44])[N:17]=2)[C:7]=1[C:19]([O:21][CH:22]([C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)[C:23]1[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1)=[O:20])(=[O:3])[CH3:2]