Methyl iodide → HCID 21475759, compound

HRID 2293039Notes

Reaction equation

HRID 2293039 reaction equation
[CH3:1][O:2][N:3]([CH3:7])[C:4]([NH2:6])=[S:5].C[I:9].[C:10](OCC)(=O)C>CN(C)C=O>[IH:9].[CH3:1][O:2][N:3]([CH3:7])[C:4](=[NH:6])[S:5][CH3:10]

Participants

5

Reactant 3

HCID 6328Methyl iodideHCID 8857Ethyl AcetateHCID 21475728HCID 21475728, compound

Product 1

HCID 21475759HCID 21475759, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

1.76 g (14.7 mmol) of N-methoxy-N-methylthiourea was dissolved in 5 ml of N,N-dimethylformamide. 2.09 g (14.7 mmol) of methyl iodide was added thereto at room temperature, and the mixture was stirred at room temperature for 15 hours. 500 ml of ethyl acetate was added thereto, and precipitated crystals were collected by filtration and then washed with ethyl acetate to obtain 2.7 g of N-methoxy-N-methyl-S-methylisothiourea hydroiodide as pale yellow crystals.

Workup

  1. customprecipitated crystals
  2. filtrationwere collected by filtration
  3. washwashed with ethyl acetate

Sources & evidence

ORD record
ord-b725d14b9a654ad68980774ba66314cb
Source dataset
uspto-grants-1997_11
Patent number
US05686390

Reaction notes

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