HRID229346

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7972

4-Methylmorpholine

C5H11NO

结构：CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F

HCID2733207

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

C11H16BF4N5O

HCID45084750

5-Ethynylthiophene-2-carboxylic acid

C7H4O2S

结构：Cc1cc(NC(=O)C2(N)CCOC2)ccc1N1CCOCC1=O

HCID68870645

未命名化合物

PRODUCTS

生成物

结构：C#Cc1ccc(C(=O)NC2(C(=O)Nc3ccc(N4CCOCC4=O)c(C)c3)CCOC2)s1

HCID11612184

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

Prepared analogously to Example 1a from 5-ethynylthiophene-2-carboxylic acid and 3-amino-N-[3-methyl-4-(3-oxomorpholin-4-yl)phenyl]tetrahydro-furan-3-carboxamide with TBTU and NMM in DMF.