反应详情

124.6 g of [N,N-bis-(3,4-dimethylphenyl)amino]benzene and 35.5 mL of DMF were placed in a three-neck flask. While stirring and cooling in ice water, 84.4 mL of phosphorus oxychloride was dropped into the flask. Upon completion of addition of drops, the mixture solution was reacted for 5 hours at 95° C., poured into 4 L of warm water, and stirred for 1 hour. The precipitate was collected and washed in a :1:1 mixture solution of ethanol/water. 4-[N,N-bis-(3,4-dimethylphenyl)amino]benzaldehyde was obtained. The yield was 107.6 g (yield rate of 79.0%).

1. additionUpon completion of addition of drops
2. customthe mixture solution was reacted for 5 hours at 95° C.
3. stirringstirred for 1 hour
4. customThe precipitate was collected
5. washwashed in a :1:1 mixture solution of ethanol/water