Sodium Iodide → HCID 57037835, compound

HRID 2295033Notes

Reaction equation

HRID 2295033 reaction equation
[C:1]1([CH:7]=[N:8][N:9]2[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][CH2:16][CH2:17]Cl)[C:10]2=[O:19])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[I-:20].[Na+]>CC(C)=O>[C:1]1([CH:7]=[N:8][N:9]2[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][CH2:16][CH2:17][I:20])[C:10]2=[O:19])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 5238Sodium IodideHCID 57006706HCID 57006706, compound

Product 1

HCID 57037835HCID 57037835, compoundYield 65%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A stirred mixture of 1-phenylmethyleneamino-3-(4-chlorobutyl)-2-imidazolidinone (36.4 g, 0.1301 mole), acetone (700 ml) and sodium iodide (42.9 g, 0.2862 mole) is heated to reflux which is maintained for 24 hours. The mixture is filtered hot, removing the solid. After cooling, the filtrate is poured into H2O (2000 ml) and stirred 1 hour. The solid is collected, washed with H2 O, and air-dried to give 31.4 g, (0.0845 mole) of 1-phenylmethyleneamino-3-(4-iodobutyl)-2-imidazolidinone.

Workup

  1. temperatureis heated
  2. temperatureto reflux which
  3. temperatureis maintained for 24 hours
  4. filtrationThe mixture is filtered hot
  5. customremoving the solid
  6. temperatureAfter cooling
  7. additionthe filtrate is poured into H2O (2000 ml)
  8. customThe solid is collected
  9. washwashed with H2 O
  10. customair-dried

Sources & evidence

ORD record
ord-9fa3d03a871449f79cb70a17d17bc0f4
Source dataset
uspto-grants-1997_11
Patent number
US05691369

Reaction notes

Loading…