反应详情

Ethyl 7-allyloxynaphthalene-2-carboxylate (6.2 g) was heated in refluxing N,N-diethylaniline for 2 hours. The solution was cooled, treated with dilute hydrochloric acid and extracted with ethyl acetate, which was then washed with dilute hydrochloric acid, and water, dried and evaporated to a solid. Crystallisation from benzene/petroleum ether (b.p. 40-60) afforded ethyl 8-allyl-7-hydroxynaphthalene-2-carboxylate (4.5 g), m.p. 115°-116°.

1. temperatureThe solution was cooled
2. extractionextracted with ethyl acetate, which
3. washwas then washed with dilute hydrochloric acid, and water
4. customdried
5. customevaporated to a solid
6. customCrystallisation from benzene/petroleum ether (b.p. 40-60)