Hydrochloric Acid → 2,4-Dihydroxy-3-propyl-benzaldehyde

HRID 2295418Notes

Reaction equation

HRID 2295418 reaction equation
[CH2:1]([C:4]1[C:10]([OH:11])=[CH:9][CH:8]=[CH:7][C:5]=1[OH:6])[CH2:2][CH3:3].Cl.C[CH2:14][O:15]CC>[C-]#N.[Zn+2].[C-]#N>[OH:11][C:10]1[C:4]([CH2:1][CH2:2][CH3:3])=[C:5]([OH:6])[CH:7]=[CH:8][C:9]=1[CH:14]=[O:15]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 2620601,3-Benzenediol, propyl-

Product 1

HCID 202829632,4-Dihydroxy-3-propyl-benzaldehyde

Reagents, catalysts & solvents 1

HCID 11186Zinc cyanide (Zn(CN)2)Catalyst

Procedure

Zinc cyanide (24 g) was added to a stirred suspension of 2-propylresorcinol (32.4 g) in dry ether (150 ml) and the resulting mixture saturated with hydrogen chloride. After being left to stand at room temperature for 30 minutes the ether was decanted and the remaining solid heated on the steam bath with water for 30 minutes.

Workup

  1. waitAfter being left
  2. customthe ether was decanted
  3. temperaturethe remaining solid heated on the steam bath with water for 30 minutes

Sources & evidence

ORD record
ord-045fb899e15c4664ac1728f746e25eee
Source dataset
uspto-grants-1984_01
Patent number
US04424231

Reaction notes

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