Mandelic Acid → Benzothiazol-2-yl-phenyl-methanol

HRID 2295485Notes

Reaction equation

HRID 2295485 reaction equation
[CH:1]1[CH:6]=[C:5]([NH2:7])[C:4]([SH:8])=[CH:3][CH:2]=1.[C:9](O)(=O)[CH:10]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[OH:11]>C1(C)C(C)=CC=CC=1>[OH:11][CH:10]([C:9]1[S:8][C:4]2[CH:3]=[CH:2][CH:1]=[CH:6][C:5]=2[N:7]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

4

Reactant 2

HCID 1292Mandelic AcidHCID 87132-Aminothiophenol

Product 1

HCID 257798Benzothiazol-2-yl-phenyl-methanol

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

A mixture of O-aminothiophenol (23.5 g.) and dl-mandelic acid (25 g.) was refluxed in xylene with a Dean-Stark tube for two days.

Sources & evidence

ORD record
ord-8a7ce0d6f6104070812b5b0220d48587
Source dataset
uspto-grants-1984_01
Patent number
US04425338

Reaction notes

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