Glutaric anhydride → HCID 15590830, compound

HRID 2295490Notes

Reaction equation

HRID 2295490 reaction equation
[CH2:1]([NH:8][CH2:9][CH2:10][C:11]1[C:19]2[C:14](=[CH:15][CH:16]=[C:17](Cl)[CH:18]=2)[NH:13][CH:12]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:21]1(=[O:28])[O:27][C:25](=[O:26])[CH2:24][CH2:23][CH2:22]1>C1C=CC=CC=1>[C:25]([CH2:24][CH2:23][CH2:22][C:21]([N:8]([CH2:9][CH2:10][C:11]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[NH:13][CH:12]=1)[CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)=[O:28])([OH:27])=[O:26]

Participants

4

Reactant 2

HCID 7940Glutaric anhydrideHCID 20474677HCID 20474677, compound

Product 1

HCID 15590830HCID 15590830, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

113 g (0.396 mol) of 3-(2-benzylaminoethyl)-5-chloroindole are dissolved in 500 ml of benzene. 45.27 g of glutaric anhydride are added in small amounts and the reaction mixture is heated at the reflux temperature for 2 hours and then left to stand overnight. It is evaporated to dryness. This gives the named product.

Workup

  1. temperaturethe reaction mixture is heated at the reflux temperature for 2 hours
  2. waitleft
  3. customIt is evaporated to dryness
  4. customThis gives the named product

Sources & evidence

ORD record
ord-0884a675153b4c7384afec2345421235
Source dataset
uspto-grants-1984_01
Patent number
US04425351

Reaction notes

Loading…