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HRID2296699

反应详情

EQUATION

反应方程式

HRID 2296699 的结构方程式

REACTANTS

反应物

3
结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：Nc1ccc(Cl)cc1C(O)(C#Cc1ccco1)C(F)(F)F
HCID54107311

未命名化合物

结构：O=C([O-])[O-].[Cs+].[Cs+].[I-].[Li+]
HCID86755963

未命名化合物

PRODUCTS

生成物

1
结构：CC[C@@H]1O[C@](C#Cc2ccoc2)(C(F)(F)F)c2cc(Cl)ccc2NC1=O
HCID56987812

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in a manner similar to the product of Example 11 except that cesium carbonate/lithium iodide rather than sodium hydride was used in the final reaction step: mp 169-170°; HRMS: Calcd. for C18H14NO3F3Cl (M+H)+: 384.061431. Found: 384.058632.

WORKUP

后处理

  1. customreaction step