Nicotinamide → HCID 18379740, compound

HRID 2299096Notes

Reaction equation

HRID 2299096 reaction equation
[C:1]([NH2:9])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[N:4][CH:3]=1.[NH:10]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[N:12]=[N:11]1.[C:19]1([CH3:29])[CH:24]=[CH:23][C:22](S(O)(=O)=O)=[CH:21][CH:20]=1>C1(C)C(C)=CC=CC=1>[N:10]1([CH:1]([NH:9][C:1](=[O:8])[C:2]2[CH:7]=[CH:6][CH:5]=[N:4][CH:3]=2)[C:2]([CH3:7])([CH3:3])[CH2:29][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[N:12]=[N:11]1

Participants

5

Reactant 3

HCID 936NicotinamideHCID 6101p-Toluenesulfonic acidHCID 178418385HCID 178418385, compound

Product 1

HCID 18379740HCID 18379740, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

The product from Example 18A, nicotinamide, benzotriazole, and p-toluenesulfonic acid in xylene were processed as described in Example 18B to provide the title compound.

Sources & evidence

ORD record
ord-e97edd7b878f45d2ba0b70e4a3b0f8cd
Source dataset
uspto-grants-2002_12
Patent number
US06495576B2

Reaction notes

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