2-Chloropropionic acid → N-(3,5-dichlorophenyl)-D,L-alanine

HRID 2299530Notes

Reaction equation

HRID 2299530 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[C:7]([Cl:9])[CH:8]=1)[NH2:5].Cl[CH:11]([CH3:15])[C:12]([OH:14])=[O:13]>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:5][CH:11]([C:12]([OH:14])=[O:13])[CH3:15])[CH:6]=[C:7]([Cl:9])[CH:8]=1

Participants

3

Reactant 2

HCID 117342-Chloropropionic acidHCID 122813,5-Dichloroaniline

Product 1

HCID 15484844N-(3,5-dichlorophenyl)-D,L-alanine

Procedure

Using the procedure set forth in U.S. Pat. No. 3,598,859 (or Example A above), N-(3,5-dichlorophenyl)-D,L-alanine was prepared using 3,5-dichloroaniline (Aldrich) and 2-chloropropionic acid (Aldrich).

Sources & evidence

ORD record
ord-7ce6cc97e5eb49348de668142a7122a3
Source dataset
uspto-grants-2002_12
Patent number
US06495693B2

Reaction notes

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