反应详情

5.2 g of hydroxylamine hydrochloride, 12.2 g of sodium acetate, and 50 ml water were added to a mixture of 20 g N-(3-formyl-4-methoxybenzyl)phthalimide and 200 ml tetrahydrofuran, and stirred at room temperature for 1 hr. It was stirred at 60° C. for 1 hr, and then evaporated. Water was added to the resulting residue, and the insoluble matters were collected by filtration. These were washed with diethyl ether to give 20 g of N-(3-hydroxyimino-4-methoxybenzyl)phthalimide.

1. stirringIt was stirred at 60° C. for 1 hr
2. customevaporated
3. additionWater was added to the resulting residue
4. filtrationthe insoluble matters were collected by filtration
5. washThese were washed with diethyl ether