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HRID2300604

反应详情

EQUATION

反应方程式

HRID 2300604 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc(C(C)=O)cc1
HCID7476

4'-Methoxyacetophenone

C9H10O2

结构：CCC(=O)CC(=O)c1ccccc1
HCID21408

Propionyl acetophenone

C11H12O2

PRODUCTS

生成物

1
结构：COc1ccc(C(=O)CC(C)=O)cc1
HCID77640

1-(4-Methoxyphenyl)butane-1,3-dione

C11H12O3

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

The title compound was prepared (as described above for Intermediate 16) from 3.0 g of 4′-methoxyacetophenone and 3.95 mL of EtOAc. Purification by recrystallization from toluene/hexane afforded the title compound: 1H NMR (400 MHz, CDCl3, enol form) δ7.70 (d, 2H, J=8.20), 7.34 (d, 2H, J=8.20), 6.17 (s, 1H), 3.87 (s, 3H), 2.17 (s, 3H); low resolution MS (ES)m/e 193.1 (MH+)

WORKUP

后处理

  1. customPurification
  2. customby recrystallization from toluene/hexane