Bis(2-Methoxyethyl)amine → HCID 18373476, compound

HRID 2301551Notes

Reaction equation

HRID 2301551 reaction equation
[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Cl:11])[C:3]=1[S:12](Cl)(=[O:14])=[O:13].[CH3:16][O:17][CH2:18][CH2:19][NH:20][CH2:21][CH2:22][O:23][CH3:24].C(N(CC)CC)C>>[CH3:16][O:17][CH2:18][CH2:19][N:20]([CH2:21][CH2:22][O:23][CH3:24])[S:12]([C:3]1[C:4]([Cl:11])=[CH:5][CH:6]=[C:7]([N+:8]([O-:10])=[O:9])[C:2]=1[Cl:1])(=[O:14])=[O:13]

Participants

4

Reactant 3

HCID 2383Bis(2-Methoxyethyl)amineHCID 8471TriethylamineHCID 234477722,6-Dichloro-3-nitrobenzene-1-sulfonyl chloride

Product 1

HCID 18373476HCID 18373476, compoundYield 89.1%

Procedure

Following the general procedure for sulfonamide formation outlined in example 15, 2,6-dichloro-3-nitrobenzenesulfonyl chloride (1.82 g, 6.26 mmol), bis(2-methoxyethyl)amine (830 mg, 6.26 mmol) and triethylamine(1.7mL, 12.52 mmol) were reacted to form the desired product (2.16 g, 89%). LC-MS (m/z) 387.2 (M+).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-83e5ecbc513e4a27bf2ab419e8eb132e
Source dataset
uspto-grants-2002_12
Patent number
US06500863B1

Reaction notes

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