Triethylamine → HCID 18373566, compound

HRID 2301557Notes

Reaction equation

HRID 2301557 reaction equation
[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Cl:11])[C:3]=1[S:12](Cl)(=[O:14])=[O:13].[CH3:16][N:17]([CH3:21])[CH2:18][CH2:19][NH2:20].C(N(CC)CC)C>>[CH3:16][N:17]([CH3:21])[CH2:18][CH2:19][NH:20][S:12]([C:3]1[C:4]([Cl:11])=[CH:5][CH:6]=[C:7]([N+:8]([O-:10])=[O:9])[C:2]=1[Cl:1])(=[O:14])=[O:13]

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 66053N,N-DimethylethylenediamineHCID 234477722,6-Dichloro-3-nitrobenzene-1-sulfonyl chloride

Product 1

HCID 18373566HCID 18373566, compoundYield 101.6%

Procedure

Following the general procedure for sulfonamide formation outlined in example 15, 2,6-dichloro-3-nitrobenzenesulfonyl chloride (400 mg, 1.38 mmol), N,N-dimethylethylenediamine (121 mg, 1.38 mmol) and triethylamine(0.39mL, 2.76 mmol) were reacted to form the crude product (480 mg) which was carried on to the hydrolysis without purification.. EI-MS (m/z) 341.88 (M−).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-543c30bb84db4dfa87b7ca4ae99590bd
Source dataset
uspto-grants-2002_12
Patent number
US06500863B1

Reaction notes

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