Triethylamine → HCID 17927831, compound

HRID 2301580Notes

Reaction equation

HRID 2301580 reaction equation
[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Cl:11])[C:3]=1[S:12](Cl)(=[O:14])=[O:13].[CH:16]1([NH2:19])[CH2:18][CH2:17]1.C(N(CC)CC)C>>[CH:16]1([NH:19][S:12]([C:3]2[C:4]([Cl:11])=[CH:5][CH:6]=[C:7]([N+:8]([O-:10])=[O:9])[C:2]=2[Cl:1])(=[O:14])=[O:13])[CH2:18][CH2:17]1

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 69828CyclopropylamineHCID 234477722,6-Dichloro-3-nitrobenzene-1-sulfonyl chloride

Product 1

HCID 17927831HCID 17927831, compoundYield 77.3%

Procedure

Following the general procedure for sulfonamide formation outlined in example 15, 2,6-dichloro-3-nitrobenzenesulfonyl chloride (1.39 g, 4.78 mmol), cyclopropylamine (273 mg, 4.78 mmol) and triethylamine(1.0 mL, 7.17 mmol) were reacted to form the desired product (1.15 g, 77%). 1H NMR (MeOD-d4): δ 7.72 (d, 1H), 7.65 (d, 1H), 2.34 (m, 1H), 0.75 (m, 4H).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-2e81449e52fd43a9aa7378871edd3f22
Source dataset
uspto-grants-2002_12
Patent number
US06500863B1

Reaction notes

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