Triethylamine → HCID 17927791, compound

HRID 2301606Notes

Reaction equation

HRID 2301606 reaction equation
[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Cl:11])[C:3]=1[S:12](Cl)(=[O:14])=[O:13].Cl.[NH2:17][CH2:18][CH:19]1[CH2:21][CH2:20]1.C(N(CC)CC)C>>[CH:19]1([CH2:18][NH:17][S:12]([C:3]2[C:4]([Cl:11])=[CH:5][CH:6]=[C:7]([N+:8]([O-:10])=[O:9])[C:2]=2[Cl:1])(=[O:14])=[O:13])[CH2:21][CH2:20]1

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 81671(Cyclopropylmethyl)ammonium chlorideHCID 234477722,6-Dichloro-3-nitrobenzene-1-sulfonyl chloride

Product 1

HCID 17927791HCID 17927791, compoundYield 84%

Procedure

Following the general procedure for sulfonamide formation outlined in example 15, 2,6-dichloro-3-nitrobenzenesulfonyl chloride (1.5 g, 5.2 mmol), aminomethyl cyclopropane hydrochloride (0.56 g, 5.2 mmol) and triethylamine (1.8mL, 12.9 mmol) were reacted to form the desired product (1.28 g, 84%). LC-MS m/z 325 (M+).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-bc834d51dab8452c9e19a0f8bdb2e92d
Source dataset
uspto-grants-2002_12
Patent number
US06500863B1

Reaction notes

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