Diethyl Ether → HCID 10997378, compound

HRID 2302171Notes

Reaction equation

HRID 2302171 reaction equation
ClC1C=C(C=CC=1)C(OO)=[O:6].[C:12]1([O:18][CH2:19][C:20](=[CH2:22])[CH3:21])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.CCOCC.C(=O)(O)[O-].[Na+]>C(Cl)(Cl)Cl>[O:6]1[C:20]([CH3:21])([CH2:19][O:18][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:22]1

Participants

6

Reactant 4

HCID 3283Diethyl EtherHCID 70297m-Chloroperbenzoic acidHCID 79893(2-Methylallyloxy)benzeneHCID 516892Sodium Bicarbonate

Product 1

HCID 10997378HCID 10997378, compoundYield 83%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

To a solution of 3-chloroperoxybenzoic acid (70% pure, 4.2 g, 17 mmol) in 40 mL of chloroform was added methallyl phenyl ether (2.5 g, 16.87 mmol). The mixture was stirred at room temperature for 5 hours then worked up by pouring into ether and sodium bicarbonate. The organic phase was washed with sodium bisulfite, sodium bicarbonate, and sodium chloride, dried over anhydrous sodium sulfate and evaporated to give 2.3 g of 1,2-epoxy-2-methyl-3-phenoxypropane.

Workup

  1. washThe organic phase was washed with sodium bisulfite, sodium bicarbonate, and sodium chloride
  2. dry with materialdried over anhydrous sodium sulfate
  3. customevaporated

Sources & evidence

ORD record
ord-11b38a11c1f449818ddaa2d168854f11
Source dataset
uspto-grants-2002_08
Patent number
US06432656B1

Reaction notes

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