2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → HCID 70103175, compound

HRID 2303323Notes

Reaction equation

HRID 2303323 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1[C:16]2[C:7](=[CH:8][C:9]3[CH2:10][CH2:11][N:12]([CH2:18][C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=4)[C:13](=[O:17])[C:14]=3[CH:15]=2)[NH:6][CH:5]=1.ClC1C(=O)C(C#N)=C(C#N)C(=O)C=1Cl>ClC1C=CC=CC=1>[NH2:1][CH2:2][CH2:3][C:4]1[CH:5]=[N:6][C:7]2[C:16]=1[CH:15]=[C:14]1[C:9](=[CH:10][CH2:11][N:12]([CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[C:13]1=[O:17])[CH:8]=2

Participants

4

Reactant 2

HCID 67752,3-Dichloro-5,6-dicyano-1,4-benzoquinoneHCID 9901595HCID 9901595, compound

Product 1

HCID 70103175HCID 70103175, compound

Reagents, catalysts & solvents 1

HCID 7964ChlorobenzeneSolvent

Procedure

A solution of 3-(2-Amino-ethyl)-6-benzyl-1,6,7,8-tetrahydro-pyrrolo[2,3-g]isoquinolin-5-one (1 mmole) and 2,3-dichloro-5,6-dicyanobenzoquinone (2 mmole) in chlorobenzene (15 mL) at reflux under nitrogen for 24 hours provides the titled compound as a yellow colored solid.

Sources & evidence

ORD record
ord-f97842e6764f4cf6af3032bed6872399
Source dataset
uspto-grants-2002_08
Patent number
US06432974B1

Reaction notes

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