反应详情

温度

90 °C

7-Methoxy-isoquinoline-N-oxide hydrochloride (38.2 g) was added in portions to phosphoryl chloride (275 mL) and the mixture heated at 90° C. for 6 h. Excess of phosphoryl chloride was removed in vacuo. The remaining white solid was washed with water, filtered and dried in vacuo.

1. customExcess of phosphoryl chloride was removed in vacuo
2. washThe remaining white solid was washed with water
3. filtrationfiltered
4. customdried in vacuo