Hydrochloric Acid → HCID 18435659, compound

HRID 2304461Notes

Reaction equation

HRID 2304461 reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1/[CH:13]=[CH:14]/[C:15]1[O:16][C:17]2[CH:23]=[CH:22][CH:21]=[CH:20][C:18]=2[N:19]=1.[NH:24]1[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1.Cl>>[N:24]1([CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2/[CH:13]=[CH:14]/[C:15]2[O:16][C:17]3[CH:23]=[CH:22][CH:21]=[CH:20][C:18]=3[N:19]=2)[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 8082PiperidineHCID 18435640HCID 18435640, compound

Product 1

HCID 18435659HCID 18435659, compoundYield 42%

Procedure

The title compound was prepared as described in Example 5 starting with (D) of Example 5 (2.5 g, 7.6 mmmol) and using piperidine in place of dibutylamine to produce 1.2 g (42% yield) of the title compound as the HCl salt, mp 230°-232° C. IR(KBr): 1600 cm−1. MS: 377(MH+). 1H NMR (DMSO): δ 7.91-6.95 (m, 10H), 3.99 (t, J=5.2 Hz, 2H), 3.10 (m, 6H), 1.75 (m, 10H).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-eec26205065740978bcbd1d654772b4c
Source dataset
uspto-grants-2002_08
Patent number
US06436939B2

Reaction notes

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